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Ambien is a widely known and often prescribed sleeping pill for insomnia. It belongs to a class of drugs called “hypnotics” and works by slowing down brain activity, which helps people fall asleep faster and sleep longer. In this article, we’ll look at Ambien’s unusual and lesser-known aspects to help you better understand this drug.

How Ambien works

Ambien is a non-benzodiazepine sedative sleeping pill, which affects gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system. However, unlike benzodiazepines, Ambien affects only certain subtypes of GABA receptors, which makes it more specific and reduces the risk of side effects.

Unusual Ambien side effects:

  • Although Ambien is usually well tolerated, some people may experience unusual side effects, such as:
  • Sleep-driving: Some people report cases of sleep-driving or performing other difficult sleep activities after taking Ambien.
  • Nocturnal gluttony: Ambien can cause uncontrollable nocturnal gluttony in some patients.
  • Amnesia: Some people may experience temporary memory loss after taking Ambien.

Mechanism of Action

Ambien is a non-benzodiazepine sedative sleeping pill, which acts on gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system. However, unlike benzodiazepines, Ambien affects only certain subtypes of GABA receptors, which makes it more specific and reduces the risk of side effects. This property makes Ambien safer and more effective for the short-term treatment of insomnia.

Rapid action and short half-life

Ambien is quickly absorbed into the bloodstream and takes effect within 30 minutes of ingestion. This allows patients to fall asleep quickly and improve sleep quality. In addition, the drug has a short half-life (about 2-3 hours), which means it is quickly eliminated from the body and does not cause drowsiness the next day.

Use in the elderly and patients with liver dysfunction

Ambien can treat insomnia in older patients because it causes fewer side effects and has a lower risk of addiction than benzodiazepines. However, in elderly patients and patients with impaired liver function, Ambien dosing may need to be adjusted because these patients may have altered metabolism of the drug.

Cautions and Counterindications

Ambien is a powerful drug; a doctor should strictly monitor its use. Here are some important cautions and counterindications to consider when using Ambien:

  • Ambien should not be taken with alcohol or other sedatives, as this can increase its effects and cause dangerous side effects.
  • Ambien can be addictive, especially with long-term use or high doses. The physician should monitor the treatment and gradually reduce the drug dose when withdrawn to avoid withdrawal symptoms.
  • Ambien is contraindicated in people with an allergy to zolpidem or other drug constituents and in patients with severe hepatic impairment or sleep apnea syndrome.
  • Pregnant and lactating women should refrain from using Ambien without prior consultation with a physician since its effects on the developing fetus and breast milk have not been adequately studied.

Alternatives to Ambien

If you have problems with side effects or Ambien does not have the desired effect, talk to your doctor to consider alternative remedies for insomnia. Here are some examples of alternatives:

  • Melatonin: a natural hormone that regulates sleep-wake and can be used as a supplement to treat insomnia.
  • Valerian: an herbal medicine that has calming properties and can help with insomnia.
  • Benzodiazepines: although they have more side effects and risk of addiction, some people may benefit from using benzodiazepines to treat insomnia.

Conclusion

Ambien is an effective sleeping pill for insomnia, but its use may have unusual side effects and cautions. If you encounter problems with Ambien, discuss it with your doctor and consider possible alternatives for treating your insomnia.